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KMID : 0829220120360040243
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Korean Journal of Oral and Maxillofacial Pathology
2012 Volume.36 No. 4 p.243 ~ p.250
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Huge Central Ossifying Fibroma on the Anterior Mandible : A Case Report
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Moon Seong-Yong
Kim Su-Gwan
Kim Hak-Kyun
Yoon Jung-Hoon
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Abstract
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The ossifying fibroma (OF), with the microscopic features of trabuclae or spherules of bone or cementum-like material in a cellular fibrous connective tissue stroma, is one of the most common benign fibro-osseous lesions in the jaw bones. The OF often occurs in patients from 20 to 40 years of age, which is a definite female predilection. The mandibles are involved far more often than the maxillas, especially the pre-molar and molar regions. It is slow-growing, bone producing, asymptomatic and well-demarcated. The OF is a disorder of odontogenesis or osteogenesis ascribed to bone marrow stroma cells (BMSCs) abnormality. However, the detailed mechanisms of OF’s oncogenesis, cytodifferentiation, and tumor progression remain unknown. In this article, we reported a huge central OF on the anterior mandible. The lesion was enucleated and peripheral ostectomy was done via intraoral approach and reconstructed with vascularized iliac block bone graft. After 25 months of follow up, the tumor had not recurred. This case shows that OF may be successfully treated by conservative surgical enucleation and peripheral ostectomy.
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KEYWORD
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Ossifying fibroma, Mandible, Surgical enucleation
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